Federer, bidding for a 16th Grand Slam title, is pencilled in for a possible quarter-final with Nikolay Davydenko, while Murray could renew his rivalry with Argentine Juan Del Potro in the last eight.
In women's play, Russian Dinara Safin takes the top seeding and opens against a wild card in the shape of Australian Olivia Rogowska, the number 167 teenager who won her lone Grand Slam match in the Paris first round last spring.
Holder Serena Williams starts with compatriot Alexa Glatch, while third-seeded sister Venus plays Vera Dushevina. Former champion Maria Sharapova has a modest 29th seeding as she comes back from nearly a year of shoulder worries.
Belgian Kim Clijsters, who lifted the trophy in 2005 a year before Sharapova, continues her comeback to tennis that began this month as she plays Viktoriya Kutuzova of Ukraine.