Comments from her and other Republicans underlined Kennedy's remarkable ability to work both sides of the political aisle, bringing in conservative support for the major pieces of legislation he is known for in health care and civil rights.

Kennedy's legacy 'stands with the greatest, the most devoted, the most patriotic men and women to ever serve in these halls', Reid said.

He noted the major accomplishments attributed to Kennedy's political skill, including health insurance for young children, federal support for needy college students, and Medicare and Medicaid, which provide health care for the aged and poor.