The team includes only one specialist spinner - Saeed Ajmal.
Asif, who tested positive for banned anabolic steroid nandrolone during the inaugural season of the Indian Premier League (IPL) last summer, is currently serving a one-year ban for doping that ends Sept 22.
The selectors have decided against keeping two specialist openers which means that wicketkeeper-batsman Kamran Akmal will open the batting with big-hitter Imran Nazir.
The team will assemble at the Gaddafi Stadium in Lahore from Sep 1 for a 10-day camp to be held under floodlights because of the fasting month of Ramadan.
Pakistan squad: Younis Khan (captain), Imran Nazir, Kamran Akmal (wicketkeeper), Mohammad Yousuf, Misbah-ul-Haq, Shoaib Malik, Umar Akmal, Fawad Alam, Shahid Afridi (vice-captain), Rana Naved-ul-Hasan, Umar Gul, Mohammad Asif, Mohammad Aamer, Rao Iftikhar Anjum, Saeed Ajmal.