Sania goes from here to Cincinnati to play in the doubles at the Western and Southern Financial Group Women's Open.
Dubois said the pictures of previous winners on the court walls inspired her to fight it out.
'I visualised myself on that wall with the others and I worked hard for it,' said an excited Dubois, ranked 129 on the WTA charts.
Third seed Marcos Baghdatis of Cyprus beat Belgium's Xavier Malisse 6-4, 6-4, in the final of the $100,000 men's event.
South Africans Rik De Voest and Kevin Anderson won the men's doubles, defeating Ramon Delgado of Paraguay and Kaes Van't Hof of the US, 6-4, 6-4.
Meanwhile, Italy's Flavia Pennetta bagged the biggest win of her career, taking the $700,000 2009 LA women's title, beating Samatha Stosur of Australia 6-4, 6-3. It was Pennetta's eight Tour title, and with it came a crystal trophy and $107,000 winner's cheque in Los Angeles Sunday
Pennetta rose to No. 12 in the rankings Monday, one spot away from her career high of No. 11. Stosur, who won $55,500, goes to a career-high No. 17.
Juan Martin Del Potro, reserving his most blistering serve in the deciding tie-breaker, fired five of his 19 aces Sunday to beat American top seed Andy Roddick 3-6, 7-5, 7-6 (8/6) and win back-to-back the Legg Mason Classic title in Washington. In the only other meeting between the two, the Argentine beat the American at the Los Angeles Open last year.